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MACROPHAGE COLONY-STIMULATING FACTOR
Descriptors Found:
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DeCS
Descriptor
English
:
Macrophage Colony-Stimulating Factor
Descriptor
Spanish
:
Factor Estimulante de Colonias de Macrófagos
Descriptor
Portuguese
:
Fator Estimulador de Colônias de Macrófagos
Synonyms
English
:
Colony-Stimulating Factor, Macrophage
Colony-Stimulating Factor 1
CSF-M
CSF-1
M-CSF
Tree Number:
D12.644.276.374.410.240.500
D12.776.395.240.500
D12.776.467.374.410.240.500
D23.529.374.410.240.500
Definition
English
:
A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the
survival
, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF is a disulfide-bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor (RECEPTOR,
MACROPHAGE COLONY-STIMULATING FACTOR
).
Indexing Annotation
English
:
DF: MCSF
See Related
English
:
Receptor, Macrophage Colony-Stimulating Factor
History Note
English
:
91
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
29035
Unique Identifier:
D016173
Occurrence in VHL
:
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DeCS
CID-10
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